Wade Wilson (Ryan Reynolds) is a former Special Forces operative who now works as a mercenary. His world comes crashing down when evil scientist Ajax (Ed Skrein) tortures, disfigures and transforms him into Deadpool. The rogue experiment leaves Deadpool with accelerated healing powers and a twisted sense of humor. With help from mutant allies Colossus and Negasonic Teenage Warhead (Brianna Hildebrand), Deadpool uses his new skills to hunt down the man who nearly destroyed his life.
Created by artist/writer Rob Liefeld and writer Fabian Nicieza, the character first appeared in The New Mutants #98 (cover-dated February 1991).
The character’s popularity has seen him feature in numerous other media. In the 2004 series Cable & Deadpool, he refers to his own scarred appearance as “Ryan Reynolds crossed with a Shar Pei”, leading to Reynolds eventually portraying the character in the 2009 film X-Men Origins: Wolverine and reprising the role in the 2016 film Deadpool.